48 articles for T Tsukamoto
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.
Tohoku University
Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors - Part 3.
Takeda Pharmaceutical
Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.
Academy of Sciences of The Czech Republic
Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold.
Johns Hopkins University
Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKC¿ inhibitors.
Takeda Pharmaceutical
D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold.
Johns Hopkins University
6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel D-Amino Acid Oxidase Inhibitors.
Johns Hopkins University
Design, synthesis and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitor.
Takeda Pharmaceutical
Reversible disulfide formation of the glutamate carboxypeptidase II inhibitor E2072 results in prolonged systemic exposures in vivo.
Johns Hopkins School of Medicine
Structure-Metabolism Relationships in the Glucuronidation of d-Amino Acid Oxidase Inhibitors.
Johns Hopkins University
Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase.
Eisai
d-Thiolactones as prodrugs of thiol-based glutamate carboxypeptidase II (GCPII) inhibitors.
Johns Hopkins University
Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase.
Johns Hopkins University
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.
Johns Hopkins University
Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.
TBA
Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffolds.
Eisai
Inhibition of xc¿?¿ transporter-mediated cystine uptake by sulfasalazine analogs.
Johns Hopkins University
The discovery and structure-activity relationships of indole-based inhibitors of glutamate carboxypeptidase II.
Eisai Research Institute
Multivalent scaffolds for affinity maturation of small molecule cell surface binders and their application to prostate tumor targeting.
Justus-Liebig-Universitat Giessen
Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold.
Academy of Sciences of the Czech Republic V.v.i.
Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.
TBA
Effects of 6-Aminonicotinic Acid Esters on the Reprogrammed Epigenetic State of Distant Metastatic Pancreatic Carcinoma.
Johns Hopkins University School of Medicine
Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II.
Guilford Pharmaceuticals
Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor.
Guilford Pharmaceuticals
Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors-Part 2.
Takeda Pharmaceutical
Phosphonate and phosphinate analogues of N-acylated gamma-glutamylglutamate. potent inhibitors of glutamate carboxypeptidase II.
Guilford Pharmaceuticals
New strategy for antedrug application: development of metalloproteinase inhibitors as antipsoriatic drugs.
Organon K.K.
Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker.
Johns Hopkins University
Design and pharmacological activity of phosphinic acid based NAALADase inhibitors.
Guilford Pharmaceuticals
Neutral sphingomyelinase 2 inhibitors based on the 4-(1H-imidazol-2-yl)-2,6-dialkoxyphenol scaffold.
Johns Hopkins University
Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists.
Eisai
Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Institute of Biotechnology of The Czech Academy of Sciences
Recent Progress in the Discovery of Allosteric Inhibitors of Kidney-Type Glutaminase.
TBA
Synthesis and biological evaluation of N alpha-(4-amino-4-deoxy-10-methylpteroyl)-DL-4,4-difluoroornithine.
University of Michigan
Synthesis and biological evaluation of DL-4,4-difluoroglutamic acid and DL-gamma,gamma-difluoromethotrexate.
University of Michigan
Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors.
Johns Hopkins University
Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids.
Tokushima University
Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain.
Academy of Sciences of The Czech Republic
Practical application of 3-substituted-2,6-difluoropyridines in drug discovery: Facile synthesis of novel protein kinase C theta inhibitors.
Takeda Pharmaceutical
Substituted tricyclic heterocycles as histamine 4 receptor inhibitors
C&C Research Laboratories
1-(dimethylamino)ethyl-substituted 6H-benzo[C]chromen-6-ones against senile dementia
Nobel IlaÇ
Pyrimidine compounds as inhibitors of protein kinases IKK epsilon and/or TBK-1, processes for their preparation, and pharmaceutical compositions containing them
Domainex