Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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12 articles for P McConnell

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase.

Pfizer

Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring.

Pfizer

Novel and selective spiroindoline-based inhibitors of Sky kinase.

Pfizer

Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.

Pfizer

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

Pfizer

Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand.

Warner-Lambert

bis-Pyridazine compounds and their use in treating cancer

Astrazeneca

Substituted acethydrazide derivative, preparation method and use thereof

Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH

Novartis

Lactams as inhibitors of rock

Bristol-Myers Squibb

Inhibitors of SYK

Hoffmann-La Roche

Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors

Novartis