The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 772K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

27 articles for AB Miller


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
43
2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.EBI
Syntex Research
19
Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite.EBI
Glaxosmithkline
15
Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene.EBI
Glaxosmithkline
25
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.EBI
Glaxosmithkline
23
FXR agonist activity of conformationally constrained analogs of GW 4064.EBI
Glaxosmithkline
40
Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064.EBI
Glaxosmithkline
12
Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands.EBI
Glaxosmithkline
24
Thiol-based angiotensin-converting enzyme 2 inhibitors: P1' modifications for the exploration of the S1' subsite.EBI
Glaxosmithkline
28
Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.EBI
Glaxosmithkline
41
Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?EBI
Glaxosmithkline
11
Ketoheterocycle-based inhibitors of cathepsin K: a novel entry into the synthesis of peptidic ketoheterocycles.EBI
Glaxosmithkline
18
P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.EBI
Glaxosmithkline
20
Acyclic cyanamide-based inhibitors of cathepsin K.EBI
Glaxosmithkline
10
A structural screening approach to ketoamide-based inhibitors of cathepsin K.EBI
Glaxosmithkline
19
Novel and potent cyclic cyanamide-based cathepsin K inhibitors.EBI
Glaxosmithkline
32
Potent and selective ketoamide-based inhibitors of cysteine protease, cathepsin K.EBI
Glaxosmithkline
17
Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions.EBI
Glaxosmithkline
27
Exploration of the P2-P3 SAR of aldehyde cathepsin K inhibitors.EBI
Glaxosmithkline
16
Structure-based design of potent retinoid X receptor alpha agonists.EBI
Glaxosmithkline
40
Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.EBI
Glaxosmithkline
39
Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.EBI
Glaxosmithkline
42
Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP).EBI
Glaxosmithkline
13
Advantageous benzofuran compositions for mental disorders or enhancementBDB
Tactogen
352
Inhibitors of Bruton's tyrosine kinaseBDB
Pharmacyclics
10
Bicyclo[3.2.1]octyl amide derivatives and uses of sameBDB
H. Lundbeck
36
Bicyclic heteroaryl derivatives as CFTR potentiatorsBDB
Cystic Fibrosis Foundation Therapeutics
10
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.BDB
Istituto Di Biostrutture E Bioimmagini-Cnr