BDBM615103 US20230271945, Compound 22

SMILES Cc1ccc(cc1)-c1[nH]c2c(F)cc(F)cc2c1CCC(=O)N[C@H]1[C@H](O)CNC1=O

InChI Key InChIKey=RCHIFIDWVHTOFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 615103   

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615103(US20230271945, Compound 22)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent