BDBM1004 N-(3-{1-[4-hydroxy-6,6-bis(2-methylpropyl)-2-oxo-5,6-dihydro-2H-pyran-3-yl]propyl}phenyl)-1-methyl-1H-imidazole-4-sulfonamide::N-[3-[1-(5,6-Dihydro-4-hydroxy-6,6-diisobutyl-2-oxo-2H-pyran-3-yl)propyl]phenyl]-1-methyl-1H-imidazole-4-sulfonamide::Tipranavir deriv. 15

SMILES CCC(C1C(=O)CC(CC(C)C)(CC(C)C)OC1=O)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1

InChI Key InChIKey=HPIWZFKLTDFQSI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1004   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1004(N-(3-{1-[4-hydroxy-6,6-bis(2-methylpropyl)-2-oxo-5...)
Affinity DataKi:  3nM ΔG°:  -11.5kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed