BDBM10199 5-[(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}-5-(thiophen-3-yl)pentyl)sulfamoyl]-2-hydroxybenzoic acid::sulfonamide analog 20

SMILES OC(=O)C[C@H](NC(=O)C(CCCCNS(=O)(=O)c1ccc(O)c(c1)C(O)=O)c1ccsc1)C=O

InChI Key InChIKey=DOAJKJHZRMKAKQ-LBAUFKAWSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10199   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM10199(5-[(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}...)
Affinity DataKi:  100nM ΔG°:  -9.54kcal/moleT: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed