BDBM102406 US8536192, I-135

SMILES COC(=O)C1(CC1)NC(=O)C1=C(O)[C@@H]2Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]24[C@@]5(O)C1)ccc3O

InChI Key InChIKey=XVCJWAXHXOUVTJ-GZIHESCCSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 102406   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Shionogi

US Patent
LigandPNGBDBM102406(US8536192, I-135)
Affinity DataKi:  1.58nM ΔG°:  -12.0kcal/moleT: 2°CAssay Description:Binding assay of opioid receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM102406(US8536192, I-135)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-DAMGO from recombinant human mu-opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Shionogi

US Patent
LigandPNGBDBM102406(US8536192, I-135)
Affinity DataKi:  9.76nM ΔG°:  -10.9kcal/moleT: 2°CAssay Description:Binding assay of opioid receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM102406(US8536192, I-135)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]-DADLE from recombinant human delta-opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed