BDBM10322 (S)-1-(Cyclohexylmethyl)-5-{1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl}isatin::1-(cyclohexylmethyl)-5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione::Isatin Sulfonamide 33

SMILES O=C1N(CC2CCCCC2)c2ccc(cc2C1=O)S(=O)(=O)N1CCC[C@H]1COc1ccccc1

InChI Key InChIKey=SHYCPWWQCBOBBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10322   

TargetCaspase-3(Human)
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10322(1-(cyclohexylmethyl)-5-{[(2S)-2-(phenoxymethyl)pyr...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed