BDBM10326 (S)-1-(4-Pyridinylmethyl)-5-{1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl}isatin::5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-1-(pyridin-4-ylmethyl)-2,3-dihydro-1H-indole-2,3-dione::Isatin Sulfonamide 37

SMILES O=C1N(Cc2ccncc2)c2ccc(cc2C1=O)S(=O)(=O)N1CCC[C@H]1COc1ccccc1

InChI Key InChIKey=DEVAZYROZHPIFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10326   

TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10326((S)-1-(4-Pyridinylmethyl)-5-{1-[2-(phenoxymethyl)p...)
Affinity DataIC50: 4.20nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10326((S)-1-(4-Pyridinylmethyl)-5-{1-[2-(phenoxymethyl)p...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed