BDBM10871 4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sulfonamide::CHEMBL266026::aromatic/heteroaromatic sulfonamide 16
SMILES Nc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O
InChI Key InChIKey=HHCXOFYGBAPOJR-UHFFFAOYSA-N
Data 104 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 104 hits for monomerid = 10871
Affinity DataKi: 1.90nMAssay Description:Inhibitory activity against murine carbonic anhydrase XIII (mCA XIII) by using CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Ki value against murine carbonic anhydrase XIIIMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 29.8nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 29.8nMAssay Description:Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of catalytic domain of human recombinant CA IXMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX.More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method.More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCA II) by using esterase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA II by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant CA2More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Ki value against human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Ki value against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration...More data for this Ligand-Target Pair
Affinity DataKi: 49nM ΔG°: -9.80kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method.More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Anopheles gambiae)
University Of Tampere And Tampere University Hospital
Curated by ChEMBL
University Of Tampere And Tampere University Hospital
Curated by ChEMBL
Affinity DataKi: 82nMAssay Description:Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair