BDBM10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1
SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
InChI Key InChIKey=BZKPWHYZMXOIDC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 106 hits for monomerid = 10880
Affinity DataKi: 2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 12nM ΔG°: -10.8kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 54nM ΔG°: -9.91kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 63nM ΔG°: -9.82kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 74nM ΔG°: -9.72kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -9.00kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+5nM ΔG°: -5.04kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.01 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 56.5nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 10 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.25 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 1.00 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 721nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.10 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.25 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.25 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.10 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 319nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 1.00 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 60.4nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 1.00 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 441nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 10 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 285nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.10 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 65.2nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.25 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 10 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 42.1nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 747nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 10 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 69.7nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 1.00 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.05 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 10 mM threitolMore data for this Ligand-Target Pair