BDBM112499 DACOMITINIB::US8623883, No. 2::WO2022090481, Example dacomitinib
SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1
InChI Key InChIKey=LVXJQMNHJWSHET-AATRIKPKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 112499
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR (unknown origin) expressed in insect cells by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of HER2 (unknown origin) expressed in insect cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.57E+6nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair