BDBM113716 US8637507, C-91

SMILES OC(=O)C1CCC(CC1)Oc1ccc(cn1)-c1ccc2N(CCOc2c1)C(=O)Nc1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=MIRFEAFVHOWPLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113716   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113716(US8637507, C-91)
Affinity DataIC50: 85nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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US Patent