BDBM113723 US8637507, B-17

SMILES Cc1cc(C(=O)Nc2ccccc2)c2ccc(cc2n1)-c1ccc(OCC(C)(C)C(O)=O)nc1

InChI Key InChIKey=GRMDIAZNKAUWLE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 113723   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113723(US8637507, B-17)
Affinity DataIC50: 275nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113723(US8637507, B-17)
Affinity DataIC50: 275nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM113723(US8637507, B-17)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human ACAT2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM113723(US8637507, B-17)
Affinity DataIC50: 69nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed