BDBM11616 5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide::N-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}acetamide::aminobenzolamide 16b::aminobenzolamide deriv. 40

SMILES CC(=O)Nc1ccc(cc1F)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=ATYLCJOUAUSNKE-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11616   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  1nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  1.20nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Universita Degli Studi Di Firenze

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  5.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  6nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Agricultural Sciences And Veterinary Medicine

LigandPNGBDBM11616(5-(4-Acetamido-3-fluorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  79nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed