BDBM11884 N-Hydroxy-4-{[4-(phenylthio)phenyl]sulfonyl}-1-(vinylmethyl)piperidine-4-carboxamide Hydrochloride::N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-1-(prop-2-en-1-yl)piperidine-4-carboxamide hydrochloride::alpha-sulfone 35e

SMILES ONC(=O)C1(CCN(CC=C)CC1)S(=O)(=O)c1ccc(Sc2ccccc2)cc1

InChI Key InChIKey=FQPCVUZCOHLRGT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11884   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11884(N-Hydroxy-4-{[4-(phenylthio)phenyl]sulfonyl}-1-(vi...)
Affinity DataKi:  0.150nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11884(N-Hydroxy-4-{[4-(phenylthio)phenyl]sulfonyl}-1-(vi...)
Affinity DataKi:  0.300nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11884(N-Hydroxy-4-{[4-(phenylthio)phenyl]sulfonyl}-1-(vi...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed