BDBM120114 US8697715, 173::US9259470, 173

SMILES CCn1cc(Nc2nccc(n2)-c2ccn([C@H](CO)c3ccc(Cl)c(F)c3)c(=O)c2)c(C)n1

InChI Key InChIKey=ULOBOPPHTKWOKZ-OAQYLSRUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 120114   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50:  5.70nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50:  5.70nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50:  18nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)
Affinity DataIC50:  18nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed