BDBM121129 A457::US8722896, (+/-)-1-Benzyl-N-(9-chloro-3,4- dihydro-2H-1,5-benzodioxepin- 7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide
SMILES CC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)C1CCN(Cc2ccccc2)C1
InChI Key InChIKey=IOXBZEKQVLIIQH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 121129
TargetProkineticin receptor 2(Cricetulus griseus (Chinese hamster))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataKi: 4.82nM ΔG°: -11.8kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
TargetProkineticin receptor 2(Cricetulus griseus (Chinese hamster))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataKi: 9.98nM ΔG°: -11.3kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Affinity DataIC50: 102nMpH: 7.5 T: 2°CAssay Description:Briefly, Chinese hamster ovary cells stably expressing the photoprotein aequorin were transiently transfected with WT or respective mutant PKR2-expre...More data for this Ligand-Target Pair
Affinity DataIC50: 40nM EC50: 7.80nMpH: 7.5 T: 2°CAssay Description:Briefly, Chinese hamster ovary cells stably expressing the photoprotein aequorin were transiently transfected with WT or respective mutant PKR2-expre...More data for this Ligand-Target Pair