BDBM13158 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione::Embelin

SMILES CCCCCCCCCC=Cc1c(O)c(O)cc(O)c1O

InChI Key InChIKey=LEMOCKLYNMZOCJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13158   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University Of Michigan

LigandPNGBDBM13158(2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dio...)
Affinity DataKi:  400nM ΔG°:  -8.63kcal/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM13158(2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dio...)
Affinity DataIC50:  4.10E+3nMAssay Description:Compound was tested for inhibiotry activity towards XIAP BIR3 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM13158(2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dio...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory concentration of compound against XIAP BIR3 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed