BDBM13775 (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one::11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione::3H-cortisol::HYDROCORTISONE::US10188667, Example 00023::[3H]cortisol::cortisol

SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO

InChI Key InChIKey=JYGXADMDTFJGBT-UHFFFAOYSA-N

Data  3 KI  11 IC50  3 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13775   

TargetGlucocorticoid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM13775([3H]cortisol | (1S,2R,10S,11S,14R,15S,17S)-14,17-d...)
Affinity DataKd:  43nMAssay Description:Displacement of 1 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed