BDBM142039 US8927577, 118::US8927577, 20::US8927577, 35

SMILES Cc1cc2cc(F)ccc2nc1NC(C1CC(C)(C)C1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key InChIKey=YZUWLDZGWNDIRB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 142039   

TargetPro-glucagon(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM142039(US8927577, 118 | US8927577, 20 | US8927577, 35)
Affinity DataKi:  14nMpH: 7.4Assay Description:The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptor. Test compoun...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM142039(US8927577, 118 | US8927577, 20 | US8927577, 35)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-glucagon from human glucagon receptor expressed in Chem-1 cell membranes after 6 to 10 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-glucagon(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM142039(US8927577, 118 | US8927577, 20 | US8927577, 35)
Affinity DataKi:  39nMpH: 7.4Assay Description:The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptor. Test compoun...More data for this Ligand-Target Pair
In DepthDetails US Patent