BDBM145920 US8957064, 48.1

SMILES COC(=O)c1cnn2cc(c(nc12)-c1ccc(CN2CCC(CC2)c2n[nH]c(n2)-c2ccccn2)cc1)-c1c(F)cccc1F

InChI Key InChIKey=ADWYMXOWUKHDBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145920   

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM145920(US8957064, 48.1)
Affinity DataIC50: 203nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM145920(US8957064, 48.1)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
In DepthDetails
US Patent