BDBM150488 US10238633, Example 162::US8987249, 162::US9713606, 162

SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc(o1)C#N

InChI Key InChIKey=MKOXMDMJBGUVAL-QOIOWGMHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 150488   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150488(US10238633, Example 162 | US8987249, 162 | US97136...)
Affinity DataIC50:  2nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150488(US10238633, Example 162 | US8987249, 162 | US97136...)
Affinity DataIC50:  2nMAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150488(US10238633, Example 162 | US8987249, 162 | US97136...)
Affinity DataIC50:  2nMpH: 6.0 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....More data for this Ligand-Target Pair
In DepthDetails US Patent