BDBM150888 US8981106, 77

SMILES Fc1ccc(NC(=O)c2ccc(SCC3CCOCC3)nc2)cc1


Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150888   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150888(US8981106, 77)
Show SMILES Fc1ccc(NC(=O)c2ccc(SCC3CCOCC3)nc2)cc1
Show InChI InChI=1S/C18H19FN2O2S/c19-15-2-4-16(5-3-15)21-18(22)14-1-6-17(20-11-14)24-12-13-7-9-23-10-8-13/h1-6,11,13H,7-10,12H2,(H,21,22)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...More data for this Ligand-Target Pair