BDBM150927 US8981106, 116

SMILES Fc1ccc(NC(=O)c2ccc(SCC(=O)c3ccco3)nc2)cc1


Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150927   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150927(US8981106, 116)
Show SMILES Fc1ccc(NC(=O)c2ccc(SCC(=O)c3ccco3)nc2)cc1
Show InChI InChI=1S/C18H13FN2O3S/c19-13-4-6-14(7-5-13)21-18(23)12-3-8-17(20-10-12)25-11-15(22)16-2-1-9-24-16/h1-10H,11H2,(H,21,23)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...More data for this Ligand-Target Pair