BDBM152637 (2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one (M5)

SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=VAXLEWGXMBDXEN-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 152637   

TargetAmine oxidase [flavin-containing] B(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM152637((2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phe...)
Affinity DataIC50: 199nMAssay Description:Inhibition of recombinant human MAOB using benzylamine as substrate after 30 mins by Amplex red based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM152637((2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAOA using p-tyramine as substrate after 30 mins by Amplex red based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM152637((2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phe...)
Affinity DataKi:  220nMpH: 7.4Assay Description:Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM152637((2E)-1-(4-methoxyphenyl)-3-[4-(trifluoromethyl)phe...)
Affinity DataKi:  4.32E+3nMpH: 7.4Assay Description:Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed