BDBM154565 N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)benzamide (21)

SMILES CC(C)(C)NCCCNC(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=UTBTYWGTMLPLJP-UHFFFAOYSA-N

Data  11 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 154565   

TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 2.20E+4nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetChromobox protein homolog 7(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetPHD finger protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetPHD finger protein 19(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetPHD finger protein 23(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetE3 ubiquitin-protein ligase UHRF1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetMBT domain-containing protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154565(N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)b...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of 53BP1 methyllysine binding domain (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)