BDBM15579 CHEMBL972::DEPRENYL::L-Deprenyl::N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine::SLG::Selegiline::US8633208, Deprenyl::US9469653, Selegiline::methyl[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-ylamine

SMILES C[C@H](Cc1ccccc1)N(C)CC#C

InChI Key InChIKey=MEZLKOACVSPNER-UHFFFAOYSA-N

Data  46 KI  207 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15579   

TargetAmine oxidase [flavin-containing] B(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 5.44E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed