BDBM15613 4-chloro-N-(2-morpholin-4-ylethyl)benzamide::4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide::Aurorix::CHEMBL86304::MCL::Moclobemide
SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1
InChI Key InChIKey=YHXISWVBGDMDLQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 96 hits for monomerid = 15613
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human MAOA by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate assessed as reduc...More data for this Ligand-Target Pair
Affinity DataIC50: 8.96E+4nMAssay Description:Competitive inhibition of MAOB in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Competitive inhibition of MAOA in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOB inhibitor selegili...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAO-A assessed as inhibition of production of hydrogen peroxide after 15 mins by Amplex Red fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI insect cells assessed as hydrogen peroxide production after 15 mins by Amp...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
Affinity DataIC50: 9.99E+6nMAssay Description:Inhibition of MAO-B in bovine brain mitochondria fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-tyramin...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as inhibition of hydrogen peroxide product...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate incubated for 15 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate incubated for 15 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BT1-TN-5B1-4 cells assessed as inhibition of production of hydrogen peroxide ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of bovine mitochondrial MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of bovine mitochondrial MAOBMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...More data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTITN-5B1-4 insect cells using p-tyramine as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataIC50: 6.06E+3nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-B using tyramine as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of human recombinant MAO-A by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.63E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.66E+3nMAssay Description:Inhibition of human recombinant MAO-A using tyramine as substrate preincubated with enzyme for 30 mins followed by incubation with substrate for 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 361nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI-TN-5B1-4 cells using p-tyramine substrate assessed as reduction in H2O2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+5nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of bovine brain MAO-B preincubated for 60 mins before substrate addition by fluorimetric methodMore data for this Ligand-Target Pair