BDBM15618 4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-((tetrahydrofuran-2-yl)methyl)-1H-pyrrole-2-carboxamide::4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-(oxolan-2-ylmethyl)-1H-pyrrole-2-carboxamide::Pyrrole Carboxamide Analog 5d

SMILES Clc1cccc(c1)-c1c[nH]nc1-c1c[nH]c(c1)C(=O)NCC1CCCO1

InChI Key InChIKey=HKKKUFBFJIIVRA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15618   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM15618(4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-((tetrahy...)
Affinity DataKi:  430nM ΔG°:  -8.82kcal/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM15618(4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-((tetrahy...)
Affinity DataKi:  2.70E+3nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by JNK3 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed