BDBM15629 N-(Benzyloxy)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1Hpyrrole-2-carboxamide::N-(benzyloxy)-4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-1H-pyrrole-2-carboxamide::Pyrrole Carboxamide Analog 5o

SMILES Clc1cccc(c1)-c1c[nH]nc1-c1c[nH]c(c1)C(=O)NOCc1ccccc1

InChI Key InChIKey=CVYVCWOKSDKRHQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15629   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM15629(N-(Benzyloxy)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-y...)
Affinity DataKi:  170nM ΔG°:  -9.38kcal/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM15629(N-(Benzyloxy)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-y...)
Affinity DataKi:  2.90E+3nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by JNK3 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed