BDBM161377 US9108956, 1::US9108956, 2::US9108956, 3::US9108956, 4::US9108956, 5

SMILES Cc1nc(C(=O)Nc2ccc(cc2)-c2ccc(cc2)C2CCC(CC(O)=O)OC2)c(o1)C(F)(F)F

InChI Key InChIKey=GORUONAPQBRBPQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 161377   

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161377(US9108956, 2 | US9108956, 3 | US9108956, 4 | US910...)
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161377(US9108956, 2 | US9108956, 3 | US9108956, 4 | US910...)
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161377(US9108956, 2 | US9108956, 3 | US9108956, 4 | US910...)
Affinity DataIC50: 820nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161377(US9108956, 2 | US9108956, 3 | US9108956, 4 | US910...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161377(US9108956, 2 | US9108956, 3 | US9108956, 4 | US910...)
Affinity DataIC50: 2.60E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent