BDBM16322 3-{[5-cyano-6-(propylamino)pyrimidin-4-yl]amino}-N-methoxy-4-methylbenzamide::5-Cyanopyrimidine Derivative 14b

SMILES CCCNc1ncnc(Nc2cc(ccc2C)C(=O)NOC)c1C#N

InChI Key InChIKey=HSQMAKZHOAZZPL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16322   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM16322(3-{[5-cyano-6-(propylamino)pyrimidin-4-yl]amino}-N...)
Affinity DataKi:  0.970nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed