BDBM164140 BDBM255252::US9062078, 270::US9637496, 270::US9695183, 270

SMILES Fc1cccc(C(=O)N2C3CCC2C(C3)Nc2nccn3c(Br)cnc23)c1-c1ncccn1

InChI Key InChIKey=BNPVELSULLCXLP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164140   

TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM164140(BDBM255252 | US9062078, 270 | US9637496, 270 | US9...)
Affinity DataKi:  145nM ΔG°:  -9.79kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM164140(BDBM255252 | US9062078, 270 | US9637496, 270 | US9...)
Affinity DataKi:  325nM ΔG°:  -9.29kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent