BDBM16653 2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzamide::CHEMBL138530::aromatic sulfonamide compound 18

SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1

InChI Key InChIKey=ARIFRHZMMVDEFJ-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 16653   

TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Universita Degli Studi Di Firenze

LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  10nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  17nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  17nMAssay Description:Inhibition of human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universita Degli Studi Di Firenze

LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  600nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universita Degli Studi Di Firenze

LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  600nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CA4) from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  950nMAssay Description:99 Tested for inhibition of human (cloned) isozyme Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM16653(2,3,4,5,6-pentafluoro-N-(4-sulfamoylphenyl)benzami...)
Affinity DataKi:  950nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed