BDBM17241 3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-5-(morpholin-4-ylmethyl)thiophene-2-carboxamide::thiophene-containing non-amidine inhibitor, 34

SMILES Clc1cc(CN2CCOCC2)sc1C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=QOHWJHLSEMXCMA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17241   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex

LigandPNGBDBM17241(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  34nM ΔG°:  -10.1kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex

LigandPNGBDBM17241(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi: >5.00E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex

LigandPNGBDBM17241(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi: >5.00E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed