BDBM173614 9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-1-yl]-b-D-ribofuranosyl]adenine (12b)

SMILES Cc1cn(Cc2cn(nn2)[C@H]2[C@@H](CO)O[C@H](C2O)N2C=NC3C2N=CN=C3N)c(=O)[nH]c1=O

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173614   

TargetRibonuclease pancreatic(Bison bison (American bison))
University Of Thessaly

LigandPNGBDBM173614(9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...)
Affinity DataKi:  6.88E+4nM ΔG°:  -5.77kcal/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
University Of Thessaly

LigandPNGBDBM173614(9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...)
Affinity DataKi:  3.65E+5nM ΔG°:  -4.76kcal/mole IC50:  5.59E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed