BDBM174948 US9096593, P-2049

SMILES COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1

InChI Key InChIKey=NSMOZFXKTHCPTQ-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 174948   

TargetCytochrome P450 3A4(Human)
Plexxikon

US Patent
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetCytochrome P450 3A4(Human)
Plexxikon

US Patent
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50:  5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent