BDBM17594 A-357300::CHEMBL352764::N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfanyl)pentanoyl]-3-chlorobenzohydrazide::bestatin-type inhibitor, 9

SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1

InChI Key InChIKey=BYBVYIPUGPZRSX-OLZOCXBDSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17594   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM17594(A-357300 | CHEMBL352764 | N'-[(2S,3R)-3-amino-2-hy...)
Affinity DataIC50:  120nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM17594(A-357300 | CHEMBL352764 | N'-[(2S,3R)-3-amino-2-hy...)
Affinity DataIC50:  5.70E+4nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM17594(A-357300 | CHEMBL352764 | N'-[(2S,3R)-3-amino-2-hy...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human MetAP2 using Met-Ala-Ser as substrate measured at 20 secs interval for 20 mins by AAO/horse radish peroxidase enzyme ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM17594(A-357300 | CHEMBL352764 | N'-[(2S,3R)-3-amino-2-hy...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human methionine aminopeptidase-2More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM17594(A-357300 | CHEMBL352764 | N'-[(2S,3R)-3-amino-2-hy...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed