BDBM175990 US10047103, 23::US9688695, 23

SMILES CCc1nc(COc2cc(OC)cc3oc(cc23)-c2cn3nc(OC)sc3n2)cs1

InChI Key InChIKey=MJFCEHWKFQBBPB-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 175990   

TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175990(US10047103, 23 | US9688695, 23)
Affinity DataEC50:  0.640nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175990(US10047103, 23 | US9688695, 23)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175990(US10047103, 23 | US9688695, 23)
Affinity DataEC50:  0.640nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent