BDBM175997 US10047103, 82::US9688695, 30::US9688695, 82

SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3cccnc3)cc(OC)cc2o1

InChI Key InChIKey=MHATUTMMUWIFBA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 175997   

TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175997(US10047103, 82 | US9688695, 30 | US9688695, 82)
Affinity DataEC50:  0.670nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175997(US10047103, 82 | US9688695, 30 | US9688695, 82)
Affinity DataEC50:  0.670nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175997(US10047103, 82 | US9688695, 30 | US9688695, 82)
Affinity DataEC50:  0.650nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM175997(US10047103, 82 | US9688695, 30 | US9688695, 82)
Affinity DataEC50:  0.650nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent