BDBM176005 US10047103, 38::US9688695, 38

SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(cc3)C(C)(C)O)cc(OC)cc2o1

InChI Key InChIKey=WILKSHHHRGQDLY-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 176005   

TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM176005(US10047103, 38 | US9688695, 38)
Affinity DataEC50:  2.5nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM176005(US10047103, 38 | US9688695, 38)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM176005(US10047103, 38 | US9688695, 38)
Affinity DataEC50:  2.5nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent