BDBM177780 US10000475, Compound 9::US9120786, 9

SMILES NC(=O)c1nc(nc(n1)-c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N1CCOCC1

InChI Key InChIKey=QXYZVVJFACMMAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177780   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM177780(US10000475, Compound 9 | US9120786, 9)
Affinity DataIC50:  596nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM177780(US10000475, Compound 9 | US9120786, 9)
Affinity DataIC50:  596nMT: 2°CAssay Description:FLIPRTETRA Sodium Dye Assay with KCl: Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant o...More data for this Ligand-Target Pair
In DepthDetails US Patent