BDBM17791 benzimidazole-urea, 19::methyl N-[6-(4-{[(3-ethylphenyl)carbamoyl]amino}phenoxy)-1H-1,3-benzodiazol-2-yl]carbamate

SMILES CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1

InChI Key InChIKey=IDBPJJQGJZOVMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17791   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17791(benzimidazole-urea, 19 | methyl N-[6-(4-{[(3-ethyl...)
Affinity DataIC50:  2.90nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM17791(benzimidazole-urea, 19 | methyl N-[6-(4-{[(3-ethyl...)
Affinity DataIC50:  18nMpH: 7.4 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed