BDBM179909 US9133125, Table D, buprenorphine

SMILES CO[C@@H]1C([C@H]2CC[C@@]11Oc3c4c(C[C@@H]5C2[C@]14CCN5CC1CC1)ccc3O)[C@](C)(O)C(C)(C)C

InChI Key InChIKey=WBANCDNNDMMESV-SKZQKDLJSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179909   

TargetMu-type opioid receptor(Homo sapiens (Human))
ALKERMES PHARMA IRELAND LIMITED

US Patent
LigandPNGBDBM179909(US9133125, Table D, buprenorphine)
Affinity DataKi:  0.410nM ΔG°:  -12.8kcal/mole IC50:  0.450nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair
In DepthDetails US Patent