BDBM18957 (2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine::AMIODARONE HYDROCHLORIDE::Amiodarone::CHEMBL633::Cordarone::L 3428::cid_441325

SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1

InChI Key InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N

Data  10 KI  37 IC50  2 EC50

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18957   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  600nMAssay Description:Concentration required to inhibit 50% of binding of [125I]-T3 to human Thyroid hormone receptor beta 1 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  650nMAssay Description:Concentration required to inhibit 50% of binding of [125I]-T3 to human Thyroid hormone receptor alpha1 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed