BDBM19135 CHEMBL209551::tert-butyl N-[(1S)-1-(cyclohexylcarbamoyl)-6-sulfanylhexyl]carbamate::thiolate analogue, 17a

SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCC1

InChI Key InChIKey=NREURQUIJSGJMZ-HNNXBMFYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 19135   

TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  36nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  1.27E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  36nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  1.14E+3nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed