BDBM1927 Carboxamide-Containing Phenprocoumon deriv. VIII::[2-[[3-[1-(4-Hydroxy-2-oxo-2H-1-benzopyran-3-yl)propyl]phenyl]amino]-1-methyl-2-oxoethyl]carbamic acid tert-butyl ester::tert-butyl N-[(1S)-1-({3-[1-(4-hydroxy-2-oxo-2H-chromen-3-yl)propyl]phenyl}carbamoyl)ethyl]carbamate

SMILES CCC(c1cccc(NC(=O)[C@H](C)NC(=O)OC(C)(C)C)c1)c1c(O)c2ccccc2oc1=O

InChI Key InChIKey=RSAXUMMUTWJKOL-BUSXIPJBSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1927   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1927(Carboxamide-Containing Phenprocoumon deriv. VIII |...)
Affinity DataKi:  170nM ΔG°:  -9.14kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
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