BDBM19473 2-Oxopropanoate::2-oxopropanoic acid::Pyruvate

SMILES CC(=O)C(O)=O

InChI Key InChIKey=LCTONWCANYUPML-UHFFFAOYSA-N

Data  4 KI  3 IC50  2 ITC

PDB links: 240 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19473   

TargetMonocarboxylate transporter 2(Rattus norvegicus)
Physiologisch-Chemisches Institut Der Eberhard-Karls-Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Affinity DataKi:  8.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of lactate uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Affinity DataKi:  2.71E+5nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Affinity DataKi:  1.19E+7nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 2A1(Homo sapiens (Human))
Albert Einstein College Of Medicine

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Affinity DataKi:  2.60E+7nMAssay Description:TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 19473   

CellAcetate Operon Repressor (C-IclR)(Escherichia coli)
University Of Toronto

SyringePNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
ITC DataΔG°: 7.20kcal/mole −TΔS°: 8.57kcal/mole ΔH°: -1.37kcal/mole logk: 6.40E+3
pH: 7.4 T: 25.00°C 
CellAcetate Operon Repressor (C-IclR)(Escherichia coli)
University Of Toronto

SyringePNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
ITC DataΔH°: -5.79kcal/mole logk: 3.10E+3
pH: 7.4 T: 25.00°C