BDBM197225 US9090621, 188::US9572811, Example 188

SMILES C[C@H](Cn1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)NC(=O)C(=CC(C)(C)N)C#N

InChI Key InChIKey=IZUCDIMZZBQYLR-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197225   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM197225(US9090621, 188 | US9572811, Example 188)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM197225(US9090621, 188 | US9572811, Example 188)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent